Thor van Heesch

PhD student of dr. J. Vreede in Computational Chemistry (2020-current).


Understanding how proteins bind to DNA provides fundamental information about biological processes, such as genome packing and transcription regulation. During my PhD I try to crack to code of how proteins bind to DNA and subsequently influence the shape and accessibility of DNA. We do this with molecular dynamics simulations and coarse-grained models that are able to describe the mechanisms of genome organization by structuring proteins.


Thor completed both his BSc (with Honors) and MSc (Cum Laude) in Chemistry at the University of Amsterdam and the Vrije Universiteit. During his studies, Thor became increasingly interested in programming and biochemistry. Now he can combine both interests in the biomolecular simulation research group of Jocelyne Vreede as a PhD candidate at the University of Amsterdam.

H-NS DNA Binding Domain bound to DNA made with iRaspa