How does the accessibility of DNA affect the expression of genes?

Dr Jocelyne Vreede of the Computational Chemistry group at the Van ‘t Hoff Institute for Molecular Sciences has received an NWO KLEIN-2 grant for a four-year project investigating how the shape and compactness of DNA affect the expression of genes. In cooperation with Prof. Willem Kegel, professor of Self-organizing Systems at Utrecht University, experimental, theoretical […]

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Loading-dependent water effects on the structural properties of water stable MOFs

According to a team of American and Dutch researchers, the structure of water-stable Metal-Organic Frameworks is less static than it might appear. In the current edition of Nature Chemistry, they report the use of in situ experiments and computational methods to investigate hydrolytic MOF stability. They explain their observations by means of a dynamic structural […]

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Negative thermal expansion design strategies in metal-organic frameworks

In a study just published in the renowned journal Advanced Functional Materials, a team of American and Dutch researchers present design strategies for adjusting the thermal expansion behaviour of microporous Metal-Organic Frameworks (MOFs). In particular, the ability to realise negative thermal expansion coefficients is of great relevance to the potential application of MOFs – for […]

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